Gui Lu er Xian Jiao is applicable for patterns of kidney yin and yang deficiency with essence and blood insufficiency. The clinical symptoms are marked by emaciation, impotence, spermatorrhea, infertility, dim-vision, and aching and weakness of waist and knees.

This formula is indicated for deficiency of kidney yang, essence, and blood. The symptoms are dry stool, clear and profuse urine, soreness and weakness of lower back and knees, dizziness, a pale tongue with a white coating, and a deep, slow and weak pulse.

1. Qi and blood deficiency of the heart and spleen marked by palpitations, amnesia, insomnia, night sweat, deficiency-heat, tiredness, reduced food intake, withered-sallow complexion, a pale tongue with a thin, white coating, and thready, weak pulses.
2. Spleen deficiency that fails to control the blood marked by hematochezia, subcutaneous purpura, flooding and spotting (beng lou), early menstruation, profuse pale menses, persistent vaginal bleeding, a pale tongue, and thready, weak pulses.

This formula is indicated for coughing and panting caused by lung heat. The symptoms are coughing, panting, and steaming heat of skin that worsens in the late afternoon, a red tongue body with a yellow coating, and a thready, rapid pulse.