Xi Jiao Di Huang Tang is indicated for the heat entering the blood level. The manifestations include:
1. Symptoms of heat harassing the heart spirit, such as fever, delirious speech, a prickly crimson colored tongue, and a thready, rapid pulse.
2. Symptoms of heat burning the blood vessels, such as purpura, spitting of blood, nosebleed, bloody stool, bloody urine, a crimson colored tongue, and a rapid pulse.
3. Symptoms of blood amassment and static heat, manic agitation, desire to rinse the mouth with water but no desire to swallow, and sloppy black stool.

Painful diarrhea due to a deficient spleen and a vigorous liver, characterized by borborygmus, abdominal pain, diarrhea with abdominal pain, pain that is relieved after diarrhea, the guan pulses of both hands not in harmony (a wiry pulse on the left hand and a moderate pulse on the right).

Zi Xue Dan is indicated for heat invading the pericardium and excessive heat generating wind. The symptoms are high fever, vexation and agitation, unconsciousness and delirium, convulsion, syncope, thirst, drinking a lot, scorched lips, dry tooth, dark urine, and constipation. The tongue is crimson with a dry, yellow coating, and a wiry, forceful pulse. Zi Xue Dan is also indicated for infantile convulsion due to excessive heat.

Shen Qi Wan is indicated for patterns of kidney yang deficiency manifesting lumbar pain, flaccidity of the lower limbs, cold sensation of the body below the waist, spasm of the lesser abdomen, dysuria or abnormally severe profuse urination at night, impotence, premature ejaculation, a pale, swollen tongue, and a deficient, weak pulse that is deep and thin at the chi position. It is also applicable for patterns of phlegm-retention, edema, xiao ke, beriberi, bladder colic, and dysuria during pregnancy, and so on.